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AvtorMulaomerović, Adaleta
Halibašić, Alma
Čičkušić, Elmir
Zavašnik-Bergant, Tina
Begić, Lejla
Kos, Janko, 1959-
Naslov Cystatin C as a potential marker for relapse in patients with non-Hodgkin B-cell lymphoma / Adaleta Mulaomerovic ... [et al.]
Vrsta/vsebinatype of material članek - sestavni del
Jezikangleški
Leto2007
Fizični opisstr. 192-197
OpombeAbstract
Bibliografija
UDK577
PovzetekThe concentration of cysteine protease inhibitor cystatin C was determined in sera from 59 patients with non-Hodgkin B-cell lymphoma using ELISA. The sera from 43 age and sex matched healthy blood donors served as controls. Cystatin C was significantly increased in sera of patients without therapy (mean 1136SE 105.7 ngžml, p = 0.00001) and with therapy (mean 1073 52 ngžml, p = 0.001) compared to controls (mean 819 28 ngžml). The highest levels were determined in sera of patients with a relapse (mean 1680 196 ngžml). By using immunofluorescence staining and confocal microscopy we determined immature dendritic cells as a major population of cystatin C positive cells inaffected lymph nodes. Our study reports for the first time that cystatin C is a potential marker for relapse in patients with non-Hodgkin B-cell lymphoma.
COBISS.SI-ID1974385
Glej publikacijo TI=Cancer letters ISSN: 0304-3835.- Vol. 248, no. 2 (2007), str. 192-197