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AvtorŽgajnar, Janez, 1963-
Perhavec, Andraž
Hočevar, Marko, 1964-
Podkrajšek, Maja
Hertl, Kristijana
Frković-Grazio, Snježana
Pohar Perme, Maja
Bešić, Nikola
Naslov Low performance of the MSKCC nomogram in preoperatively ultrasonically negative axillary lymph node in breast cancer patients / Janez Žgajnar ... [et al.]
Vrsta/vsebinatype of material članek - sestavni del
Jezikangleški
Leto2007
Fizični opisstr. 547-553
Opombe24 ref.
BSDOCID134483
Predmetne oznakeBreast Neoplasms
Lymphatic Metastasis - Ultrasonography
Axilla
Prognosis
Dojka, novotvorbe
Limfatična metastaza
Pazduha
Prognoza
URNdoi:10.1002/jso.20835
PovzetekBackgrouds and objectives: In order to predict the nonsentinel lymph node (NSLN) metastases in sentinel lymph node (SLN) positive patients a nomogram was created at the Memorial Sloan Kettering Cancer Centre (MSKCC). The aim ofour study was to validate the MSKCC nomogram in patients grouped by the preoperative ultrasound (US) examination of the axillary lymph nodes. Methods:The MSKCC nomogram was validated separately in three groups of patients: (US-0) only clinically preoperatively negative axillary lymph nodes (126 patients), (US-1) US negative axillary lymph nodes (109 patients), and (US-2) US suspicious but fine needle aspiration biopsy (FNAB) negative axillary lymph nodes (41 patients). Results: The predicted probability underestimates the actual probability with the mean absolute error equal to 0.116 in the US-0 group (P = 0.003), and overestimates the actual probability (mean absolute error equal to 0.084) in US-1 group (P = 0.033) and US-2 group (mean absolute error is 0.110) (P = 0.275). Conclusion: We found that the MSKCC nomogram overestimates the probability of the NSLN metastases in breast cancer patients with (i) preoperatively US negative or (ii) US suspicious, but FNAB negative axillary lymph nodes. We also found that MSKCC nomogram has only limited value in patients with only clinically negative axillary lymph nodes.
COBISS.SI-ID23417561
Glej publikacijo TI=Journal of surgical oncology ISSN: 0022-4790.- Vol. 96, no. 7 (2007), str. 547-553