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AvtorMurovec, Boštjan
Tiedje, James M.
Stres, Blaž
Naslov DNA encoding for an efficient 'Omics processing / Boštjan Murovec, James M. Tiedje, Blaž Stres
Vrsta/vsebinatype of material članek - sestavni del
Jezikangleški
Leto2010
Fizični opisstr. 175-190
OpombeAbstract
Predmetne oznake (nekontrolirane)molekularna genetika / DNK / sekvence / bioinformatika
UDK575
Doi/ISAN10.1016/j.cmpb.2010.03.014
URLhttp://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T5J-500SR9R-1&_user=4...
PovzetekThe exponential growth of available DNA sequences and the increased interoperability of biological information is triggering intergoivernmental efforts aimed at increasing the access, dissemination, and analysis of sequence data. Achieving the efficient storage and processing of DNA material is an important goal that parallels well with the foreseen coding standardization on the horizon. This paper proposes novel coding approaches, for both the dissemination and processing of sequences, where the speed of the DNA processing is shown to be boosted by exploring more than the normally utilized eight bits for encoding a single nucleotide. Further gains are achived by encoding the nucleotides together with their trailing alignament information as a single 64-bit data structure. the paper also proposes a slight modification to the established FASTA scheme in order to improve on its representation of alignament information. The significance of the proposition is confirmed by the encouraging results from empirical tests.
COBISS.SI-ID2625416
Glej publikacijo TI=Computer methods and programs in biomedicine ISSN: 0169-2607.- Vol. 100, no. 2 (2010), str. 175-190

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